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Celiac Disease Research Center (CeliRes)

Publications

2024

  1. Mars, N, Kerminen, S, Tamlander, M, Pirinen, M, Jakkula, E, Aaltonen, K et al.. Comprehensive Inherited Risk Estimation for Risk-Based Breast Cancer Screening in Women. J Clin Oncol. 2024; :JCO2300295. doi: 10.1200/JCO.23.00295. PubMed PMID:38422475 .
  2. Peltola, M, Kaukinen, K, Basnyat, P, Raitanen, J, Haimila, K, Liimatainen, S et al.. Hippocampal sclerosis is associated with celiac disease type immunity in patients with drug-resistant temporal lobe epilepsy. J Neurol. 2024; :. doi: 10.1007/s00415-024-12210-w. PubMed PMID:38337123 .
  3. Kurppa, K, Mulder, C, Stordal, K, Kaukinen, K. Celiac Disease Affects 1% of Global Population-Who Will Manage All These Patients? What Are Criteria to Prioritize Along Risk for Complications?. Gastroenterology. 2024; :. doi: 10.1053/j.gastro.2023.12.026. PubMed PMID:38290622 .
  4. Youssef, O, Loukola, A, Zidi-Mouaffak, YHS, Tamlander, M, Ruotsalainen, S, Kilpeläinen, E et al.. High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases. Lab Invest. 2024;104 (4):100325. doi: 10.1016/j.labinv.2024.100325. PubMed PMID:38220043 .
  5. Nurkkala, JM, Aittokallio, J, FinnGen
    , Kauko, A, Niiranen, T. Sex-specific genetic risks for adverse outcomes after coronary revascularization procedures. Interdiscip Cardiovasc Thorac Surg. 2024;38 (1):. doi: 10.1093/icvts/ivae006. PubMed PMID:38216540 PubMed Central PMC10799751.
  6. Katunin, E, Aitokari, L, Kivelä, L, Ilus, T, Huhtala, H, Kaukinen, K et al.. Measured levels of positive transglutaminase 2 antibodies are not associated with presentation or incidental endoscopic findings at celiac disease diagnosis. Scand J Gastroenterol. 2024;59 (4):419-424. doi: 10.1080/00365521.2023.2298709. PubMed PMID:38164975 .
  7. Taavela, J, Kurppa, K, Jääskeläinen, T, Kaartinen, NE, Rissanen, H, Huhtala, H et al.. Trends in the prevalence rates and predictive factors of coeliac disease: A long-term nationwide follow-up study. Aliment Pharmacol Ther. 2024;59 (3):372-379. doi: 10.1111/apt.17803. PubMed PMID:37946663 .

Search PubMed

2023

  1. Nurmi, AK, Pelttari, LM, Kiiski, JI, Khan, S, Nurmikolu, M, Suvanto, M et al.. NTHL1 is a recessive cancer susceptibility gene. Sci Rep. 2023;13 (1):21127. doi: 10.1038/s41598-023-47441-w. PubMed PMID:38036545 PubMed Central PMC10689455.
  2. Taavela, J, Kurppa, K, Jääskeläinen, T, Kaartinen, NE, Rissanen, H, Huhtala, H et al.. Trends in the prevalence rates and predictive factors of coeliac disease: A long-term nationwide follow-up study. Aliment Pharmacol Ther. 2024;59 (3):372-379. doi: 10.1111/apt.17803. PubMed PMID:37946663 .
  3. Ahonen, I, Laurikka, P, Koskimaa, S, Huhtala, H, Lindfors, K, Kaukinen, K et al.. Prevalence of vomiting and nausea and associated factors after chronic and acute gluten exposure in celiac disease. BMC Gastroenterol. 2023;23 (1):301. doi: 10.1186/s12876-023-02934-w. PubMed PMID:37674120 PubMed Central PMC10481613.
  4. Julkunen, V, Schwarz, C, Kalapudas, J, Hallikainen, M, Piironen, AK, Mannermaa, A et al.. A FinnGen pilot clinical recall study for Alzheimer’s disease. Sci Rep. 2023;13 (1):12641. doi: 10.1038/s41598-023-39835-7. PubMed PMID:37537264 PubMed Central PMC10400697.
  5. Turjanmaa, E, Hervonen, K, Huhtala, H, Arnala, S, Reunala, T, Kaukinen, K et al.. Patient-reported burden of skin disorders in coeliac disease. Scand J Gastroenterol. 2023;58 (12):1391-1397. doi: 10.1080/00365521.2023.2236263. PubMed PMID:37477901 .
  6. Nilsson, N, Leivo, J, Collin, P, Koskinen, I, Kaukinen, K, Huhtala, H et al.. Risk of vascular diseases in patients with dermatitis herpetiformis and coeliac disease: a long-term cohort study. Ann Med. 2023;55 (1):2227423. doi: 10.1080/07853890.2023.2227423. PubMed PMID:37378421 PubMed Central PMC10308869.
  7. Viippola, E, Kuitunen, S, Rodosthenous, RS, Vabalas, A, Hartonen, T, Vartiainen, P et al.. Data Resource Profile: Nationwide registry data for high-throughput epidemiology and machine learning (FinRegistry). Int J Epidemiol. 2023;52 (4):e195-e200. doi: 10.1093/ije/dyad091. PubMed PMID:37365732 PubMed Central PMC10396416.
  8. Ågren, R, Patil, S, Zhou, X, FinnGen., Sahlholm, K, Pääbo, S et al.. Major Genetic Risk Factors for Dupuytren’s Disease Are Inherited From Neandertals. Mol Biol Evol. 2023;40 (6):. doi: 10.1093/molbev/msad130. PubMed PMID:37315093 PubMed Central PMC10266526.
  9. Jones, SE, Maisha, FI, Strausz, SJ, Lammi, V, Cade, BE, Tervi, A et al.. The public health impact of poor sleep on severe COVID-19, influenza and upper respiratory infections. EBioMedicine. 2023;93 :104630. doi: 10.1016/j.ebiom.2023.104630. PubMed PMID:37301713 PubMed Central PMC10248098.
  10. Tyrmi, JS, Kaartokallio, T, Lokki, AI, Jääskeläinen, T, Kortelainen, E, Ruotsalainen, S et al.. Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy. JAMA Cardiol. 2023;8 (7):674-683. doi: 10.1001/jamacardio.2023.1312. PubMed PMID:37285119 PubMed Central PMC10248811.
  11. Miller, EC, Kauko, A, Tom, SE, Laivuori, H, Niiranen, T, Bello, NA et al.. Risk of Midlife Stroke After Adverse Pregnancy Outcomes: The FinnGen Study. Stroke. 2023;54 (7):1798-1805. doi: 10.1161/STROKEAHA.123.043052. PubMed PMID:37212139 PubMed Central PMC10330298.
  12. Ollila, HM, Sharon, E, Lin, L, Sinnott-Armstrong, N, Ambati, A, Yogeshwar, SM et al.. Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nat Commun. 2023;14 (1):2709. doi: 10.1038/s41467-023-36120-z. PubMed PMID:37188663 PubMed Central PMC10185546.
  13. Sliz, E, Tyrmi, JS, Rahmioglu, N, Zondervan, KT, Becker, CM, FinnGen et al.. Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata. Nat Commun. 2023;14 (1):542. doi: 10.1038/s41467-023-35974-7. PubMed PMID:36726022 PubMed Central PMC9892568.

Search PubMed

2022

 

  1. Pohjonen, JT, Kaukinen, KM, Metso, MJ, Nurmi, RK, Huhtala, HS, Pörsti, IH et al.. Presence of gastrointestinal symptoms in IgA nephropathy: a cross-sectional study. BMC Nephrol. 2022;23 (1):395. doi: 10.1186/s12882-022-03019-8. PubMed PMID:36482351 PubMed Central PMC9733402.
  2. Tauschi, R, Eurén, A, Vuorela, N, Koskimaa, S, Huhtala, H, Kaukinen, K et al.. Association of concomitant autoimmunity with the disease features and long-term treatment and health outcomes in Celiac disease. Front Med (Lausanne). 2022;9 :1055135. doi: 10.3389/fmed.2022.1055135. PubMed PMID:36465913 PubMed Central PMC9709120.
  3. Virta, J, Hannula, M, Lindfors, K, Tamminen, I, Taavela, J, Huhtala, H et al.. Validation of the X-ray microtomography in the assessment of duodenal morphometry and surface area in celiac disease. Front Immunol. 2022;13 :945197. doi: 10.3389/fimmu.2022.945197. PubMed PMID:36211435 PubMed Central PMC9539806.
  4. Rodosthenous, RS, Niemi, MEK, Kallio, L, Perala, M, Terho, P, Knopp, T et al.. Recontacting biobank participants to collect lifestyle, behavioural and cognitive information via online questionnaires: lessons from a pilot study within FinnGen. BMJ Open. 2022;12 (10):e064695. doi: 10.1136/bmjopen-2022-064695. PubMed PMID:36198465 PubMed Central PMC9535212.
  5. Ruuskanen, A, Kaukinen, K. Reply. J Gastrointestin Liver Dis. 2022;31 (3):358-359. doi: 10.15403/jgld-4568. PubMed PMID:36112713 .
  6. Nurmi, R, Pasternack, C, Salmi, T, Hervonen, K, Koskinen, I, Järvelin, J et al.. Authors’ reply: The risk of renal comorbidities in celiac disease patients depends on the phenotype of celiac disease. J Intern Med. 2022;292 (5):842-843. doi: 10.1111/joim.13562. PubMed PMID:36065566 .
  7. Ruotsalainen, SE, Surakka, I, Mars, N, Karjalainen, J, Kurki, M, Kanai, M et al.. Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis. Commun Biol. 2022;5 (1):802. doi: 10.1038/s42003-022-03552-0. PubMed PMID:35978133 PubMed Central PMC9385630.
  8. Repo, M, Kurppa, K, Huhtala, H, Luostarinen, L, Kaukinen, K, Kivelä, L et al.. Significance of low ferritin without anaemia in screen-detected, adult coeliac disease patients. J Intern Med. 2022;292 (6):904-914. doi: 10.1111/joim.13548. PubMed PMID:35925673 PubMed Central PMC9805163.
  9. Vuolle, S, Laurikka, P, Repo, M, Huhtala, H, Kaukinen, K, Kurppa, K et al.. Persistent symptoms are diverse and associated with health concerns and impaired quality of life in patients with paediatric coeliac disease diagnosis after transition to adulthood. BMJ Open Gastroenterol. 2022;9 (1):. doi: 10.1136/bmjgast-2022-000914. PubMed PMID:35820709 PubMed Central PMC9277401.
  10. Laurikka, P, Kivelä, L, Kurppa, K, Kaukinen, K. Review article: Systemic consequences of coeliac disease. Aliment Pharmacol Ther. 2022;56 Suppl 1 (Suppl 1):S64-S72. doi: 10.1111/apt.16912. PubMed PMID:35815828 PubMed Central PMC9543231.
  11. Rostami, K, Ensari, A, Marsh, MN, Srivastava, A, Villanacci, V, Carroccio, A et al.. Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity: A Multicentre Study. Nutrients. 2022;14 (12):. doi: 10.3390/nu14122487. PubMed PMID:35745217 PubMed Central PMC9230100.
  12. Kivelä, L, Eurén, A, Repo, M, Huhtala, H, Kaukinen, K, Kurppa, K et al.. Coexisting Type 1 Diabetes, Persistent Symptoms, and Financial Issues Associate With Poorer Adherence to a Gluten-Free Diet in Celiac Disease After Transition From Pediatrics to Adult Care. Front Nutr. 2022;9 :883220. doi: 10.3389/fnut.2022.883220. PubMed PMID:35719146 PubMed Central PMC9200750.
  13. Nurmi, R, Pasternack, C, Salmi, T, Hervonen, K, Koskinen, I, Järvelin, J et al.. The risk of renal comorbidities in celiac disease patients depends on the phenotype of celiac disease. J Intern Med. 2022;292 (5):779-787. doi: 10.1111/joim.13532. PubMed PMID:35713926 PubMed Central PMC9796855.
  14. Schiepatti, A, Sanders, DS, Baiardi, P, Caio, G, Ciacci, C, Kaukinen, K et al.. Nomenclature and diagnosis of seronegative coeliac disease and chronic non-coeliac enteropathies in adults: the Paris consensus. Gut. 2022;71 (11):2218-2225. doi: 10.1136/gutjnl-2021-326645. PubMed PMID:35676085 PubMed Central PMC9554081.
  15. Paavola, S, Kurppa, K, Huhtala, H, Saavalainen, P, Lindfors, K, Kaukinen, K et al.. Coeliac disease re-screening among once seronegative at-risk relatives: A long-term follow-up study. United European Gastroenterol J. 2022;10 (6):585-593. doi: 10.1002/ueg2.12255. PubMed PMID:35611878 PubMed Central PMC9278577.
  16. Koskinen, I, Hervonen, K, Huhtala, H, Pasternack, C, Salmi, T, Reunala, T et al.. Mortality and causes of death in different celiac disease phenotypes during long-term follow-up. Dig Liver Dis. 2022;54 (11):1502-1507. doi: 10.1016/j.dld.2022.04.016. PubMed PMID:35589505 .
  17. Pasternack, C, Hervonen, K, Mansikka, E, Reunala, T, Kaukinen, K, Salmi, T et al.. Sex-differences in Gluten-free Dietary Adherence and Clinical Symptoms in Patients with Long-term Treated Dermatitis Herpetiformis. Acta Derm Venereol. 2022;102 :adv00713. doi: 10.2340/actadv.v102.1072. PubMed PMID:35393627 PubMed Central PMC9558333.
  18. Ruuskanen, AT, Luostarinen, L, Huhtala, H, Valve, R, Kaukinen, K. Clinical Relevance of Anti-Gliadin Seropositivity in the Ageing Population: A Long-term Follow-up Study. J Gastrointestin Liver Dis. 2022;31 (1):11-17. doi: 10.15403/jgld-4025. PubMed PMID:35306543 .
  19. Tamlander, M, Mars, N, Pirinen, M, FinnGen, Widén, E, Ripatti, S et al.. Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes. Commun Biol. 2022;5 (1):158. doi: 10.1038/s42003-021-02996-0. PubMed PMID:35197564 PubMed Central PMC8866413.
  20. Saari, J, Siddique, F, Korpela, S, Mäntylä, E, Ihalainen, TO, Kaukinen, K et al.. Toward Xeno-Free Differentiation of Human Induced Pluripotent Stem Cell-Derived Small Intestinal Epithelial Cells. Int J Mol Sci. 2022;23 (3):. doi: 10.3390/ijms23031312. PubMed PMID:35163236 PubMed Central PMC8835723.
  21. Ibaid, I, Hussien, M, Kaukinen, K, Sabir, O, Elmekki, M, Musa, A et al.. Role of HLA-DQ typing and antitissue transglutaminase antibody titres in diagnosing coeliac disease among Sudanese children with type 1 diabetes mellitus. BMJ Open Gastroenterol. 2022;9 (1):. doi: 10.1136/bmjgast-2021-000735. PubMed PMID:35074908 PubMed Central PMC8788197.

Search PubMed

2021

 

  1. Airaksinen, L, Cerqueira, JX, Huhtala, H, Saavalainen, P, Yohannes, DA, Mäki, M et al.. Dissecting the contribution of single nucleotide polymorphisms in and genomic regions to the celiac disease phenotype. J Transl Autoimmun. 2021;4 :100128. doi: 10.1016/j.jtauto.2021.100128. PubMed PMID:34901814 PubMed Central PMC8640869.
  2. Paavola, S, Kaukinen, K, Kurppa, K. Editorial: coeliac disease-it’s a family affair. Authors’ reply. Aliment Pharmacol Ther. 2021;54 (7):969. doi: 10.1111/apt.16584. PubMed PMID:34506653 .
  3. Pasternack, C, Hervonen, K, Mansikka, E, Reunala, T, Collin, P, Kaukinen, K et al.. Persistent Skin Symptoms after Diagnosis and on a Long-term Gluten-free Diet in Dermatitis Herpetiformis. Acta Derm Venereol. 2021;101 (9):adv00555. doi: 10.2340/00015555-3914. PubMed PMID:34490466 PubMed Central PMC9425629.
  4. Palomäki, A, FinnGen Rheumatology Clinical Expert Group, Palotie, A, Koskela, J, Eklund, KK, Pirinen, M et al.. Lifetime risk of rheumatoid arthritis-associated interstitial lung disease in mutation carriers. Ann Rheum Dis. 2021;80 (12):1530-1536. doi: 10.1136/annrheumdis-2021-220698. PubMed PMID:34344703 PubMed Central PMC8600604.
  5. Paavola, S, Lindfors, K, Kivelä, L, Cerqueira, J, Huhtala, H, Saavalainen, P et al.. Presence of high-risk HLA genotype is the most important individual risk factor for coeliac disease among at-risk relatives. Aliment Pharmacol Ther. 2021;54 (6):805-813. doi: 10.1111/apt.16534. PubMed PMID:34278595 .
  6. O’Connell, J, Murray, JA, Kaukinen, K. Uncertain Diagnosis of Celiac Disease and Implications for Management. N Engl J Med. 2021;384 (24):2346-2348. doi: 10.1056/NEJMclde2102480. PubMed PMID:34133866 .
  7. Zekavat, SM, Lin, SH, Bick, AG, Liu, A, Paruchuri, K, Wang, C et al.. Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection. Nat Med. 2021;27 (6):1012-1024. doi: 10.1038/s41591-021-01371-0. PubMed PMID:34099924 PubMed Central PMC8245201.
  8. Nurmi, R, Korponay-Szabó, I, Laurila, K, Huhtala, H, Niemelä, O, Mustonen, J et al.. Celiac Disease-Type Tissue Transglutaminase Autoantibody Deposits in Kidney Biopsies of Patients with IgA Nephropathy. Nutrients. 2021;13 (5):. doi: 10.3390/nu13051594. PubMed PMID:34064541 PubMed Central PMC8150858.
  9. Alakoski, A, Pasternack, C, Reunala, T, Kaukinen, K, Huhtala, H, Mansikka, E et al.. Anaemia in Dermatitis Herpetiformis: Prevalence and Associated Factors at Diagnosis and One-year Follow-up. Acta Derm Venereol. 2021;101 (4):adv00443. doi: 10.2340/00015555-3795. PubMed PMID:33846758 PubMed Central PMC9364257.
  10. Yohannes, DA, Kaukinen, K, Kurppa, K, Saavalainen, P, Greco, D. Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences. BMC Bioinformatics. 2021;22 (1):159. doi: 10.1186/s12859-021-04087-7. PubMed PMID:33765908 PubMed Central PMC7993519.
  11. Käräjämäki, AJ, Taavela, J, Nielsen, C, Lönnqvist, M, Svartbäck, M, Kaukinen, K et al.. Celiac disease antibody levels reflect duodenal mucosal damage but not clinical symptoms. Scand J Gastroenterol. 2021;56 (5):514-519. doi: 10.1080/00365521.2021.1899278. PubMed PMID:33705679 .
  12. Repo, M, Hannula, M, Taavela, J, Hyttinen, J, Isola, J, Hiltunen, P et al.. Iron Transporter Protein Expressions in Children with Celiac Disease. Nutrients. 2021;13 (3):. doi: 10.3390/nu13030776. PubMed PMID:33673530 PubMed Central PMC7997288.
  13. Cerqueira, JXM, Saavalainen, P, Kurppa, K, Laurikka, P, Huhtala, H, Nykter, M et al.. Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes. J Hum Genet. 2021;66 (6):613-623. doi: 10.1038/s10038-020-00888-5. PubMed PMID:33446885 PubMed Central PMC8144013.
  14. Kurppa, K, Kivelä, L, Kaukinen, K. Letter: no-biopsy pathway for diagnosing adult coeliac disease-authors’ reply. Aliment Pharmacol Ther. 2021;53 (2):359. doi: 10.1111/apt.16195. PubMed PMID:33368505 .
  15. Nurmi, R, Pohjonen, J, Metso, M, Pörsti, I, Niemelä, O, Huhtala, H et al.. Prevalence of Inflammatory Bowel Disease and Celiac Disease in Patients with IgA Nephropathy over Time. Nephron. 2021;145 (1):78-84. doi: 10.1159/000511555. PubMed PMID:33271538 .
  16. Kaukinen, K. Updates on systemic consequences of coeliac disease. Nat Rev Gastroenterol Hepatol. 2021;18 (2):87-88. doi: 10.1038/s41575-020-00387-0. PubMed PMID:33199835 .
  17. Kurki, A, Kemppainen, E, Laurikka, P, Kaukinen, K, Lindfors, K. The use of peripheral blood mononuclear cells in celiac disease diagnosis and treatment. Expert Rev Gastroenterol Hepatol. 2021;15 (3):305-316. doi: 10.1080/17474124.2021.1850262. PubMed PMID:33176106 .
  18. Airaksinen, L, Myllymäki, L, Kaukinen, K, Saavalainen, P, Huhtala, H, Lindfors, K et al.. Differences Between Familial and Sporadic Celiac Disease. Dig Dis Sci. 2021;66 (6):1981-1988. doi: 10.1007/s10620-020-06490-1. PubMed PMID:32705440 PubMed Central PMC8163668.

Search PubMed

2020

 

  1. Yohannes, DA, de Kauwe, A, Kaukinen, K, Kurppa, K, Mäki, M, Anderson, RP et al.. Effects of Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease. Front Immunol. 2020;11 :594243. doi: 10.3389/fimmu.2020.594243. PubMed PMID:33362776 PubMed Central PMC7759501.
  2. Airaksinen, L, Laurikka, P, Huhtala, H, Kurppa, K, Salmi, T, Saavalainen, P et al.. Influence of HLA-DQ2.5 Dose on Clinical Picture of Unrelated Celiac Disease Patients. Nutrients. 2020;12 (12):. doi: 10.3390/nu12123775. PubMed PMID:33317091 PubMed Central PMC7764246.
  3. Nurmi, R, Pohjonen, J, Metso, M, Pörsti, I, Niemelä, O, Huhtala, H et al.. Prevalence of Inflammatory Bowel Disease and Celiac Disease in Patients with IgA Nephropathy over Time. Nephron. 2021;145 (1):78-84. doi: 10.1159/000511555. PubMed PMID:33271538 .
  4. Kurki, A, Kemppainen, E, Laurikka, P, Kaukinen, K, Lindfors, K. The use of peripheral blood mononuclear cells in celiac disease diagnosis and treatment. Expert Rev Gastroenterol Hepatol. 2021;15 (3):305-316. doi: 10.1080/17474124.2021.1850262. PubMed PMID:33176106 .
  5. Nätynki, A, Tuusa, J, Hervonen, K, Kaukinen, K, Lindgren, O, Huilaja, L et al.. Autoantibodies Against the Immunodominant Bullous Pemphigoid Epitopes Are Rare in Patients With Dermatitis Herpetiformis and Coeliac Disease. Front Immunol. 2020;11 :575805. doi: 10.3389/fimmu.2020.575805. PubMed PMID:33072118 PubMed Central PMC7544946.
  6. Ylönen, V, Lindfors, K, Repo, M, Huhtala, H, Fuchs, V, Saavalainen, P et al.. Non-Biopsy Serology-Based Diagnosis of Celiac Disease in Adults Is Accurate with Different Commercial Kits and Pre-Test Probabilities. Nutrients. 2020;12 (9):. doi: 10.3390/nu12092736. PubMed PMID:32911716 PubMed Central PMC7551634.
  7. Koskimaa, S, Kivelä, L, Arvola, T, Hiltunen, P, Huhtala, H, Kaukinen, K et al.. Clinical characteristics and long-term health in celiac disease patients diagnosed in early childhood: Large cohort study. Dig Liver Dis. 2020;52 (11):1315-1322. doi: 10.1016/j.dld.2020.08.010. PubMed PMID:32900652 .
  8. Virta, J, Hannula, M, Tamminen, I, Lindfors, K, Kaukinen, K, Popp, A et al.. X-ray microtomography is a novel method for accurate evaluation of small-bowel mucosal morphology and surface area. Sci Rep. 2020;10 (1):13164. doi: 10.1038/s41598-020-69487-w. PubMed PMID:32753621 PubMed Central PMC7403326.
  9. Airaksinen, L, Myllymäki, L, Kaukinen, K, Saavalainen, P, Huhtala, H, Lindfors, K et al.. Differences Between Familial and Sporadic Celiac Disease. Dig Dis Sci. 2021;66 (6):1981-1988. doi: 10.1007/s10620-020-06490-1. PubMed PMID:32705440 PubMed Central PMC8163668.
  10. Koskinen, I, Virta, LJ, Huhtala, H, Ilus, T, Kaukinen, K, Collin, P et al.. Overall and Cause-Specific Mortality in Adult Celiac Disease and Dermatitis Herpetiformis Diagnosed in the 21st Century. Am J Gastroenterol. 2020;115 (7):1117-1124. doi: 10.14309/ajg.0000000000000665. PubMed PMID:32618663 .
  11. Taurio, J, Järvinen, J, Hautaniemi, EJ, Eräranta, A, Viitala, J, Nordhausen, K et al.. Team-based “Get-a-Grip” lifestyle management programme in the treatment of obesity. Prev Med Rep. 2020;19 :101119. doi: 10.1016/j.pmedr.2020.101119. PubMed PMID:32461881 PubMed Central PMC7242875.
  12. Viitasalo, L, Iltanen, S, Huhtala, H, Saavalainen, P, Kaukinen, K, Lindfors, K et al.. First-degree Relatives of Celiac Disease Patients Have Increased Seroreactivity to Serum Microbial Markers. Nutrients. 2020;12 (4):. doi: 10.3390/nu12041073. PubMed PMID:32294897 PubMed Central PMC7230150.
  13. Alakoski, A, Hervonen, K, Mansikka, E, Reunala, T, Kaukinen, K, Kivelä, L et al.. The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis. Nutrients. 2020;12 (4):. doi: 10.3390/nu12041060. PubMed PMID:32290504 PubMed Central PMC7230654.
  14. Kivelä, L, Hekkala, S, Huhtala, H, Kaukinen, K, Kurppa, K. Lack of long-term follow-up after paediatric-adult transition in coeliac disease is not associated with complications, ongoing symptoms or dietary adherence. United European Gastroenterol J. 2020;8 (2):157-166. doi: 10.1177/2050640619900077. PubMed PMID:32213072 PubMed Central PMC7079270.
  15. Kröger, S, Kurppa, K, Repo, M, Huhtala, H, Kaukinen, K, Lindfors, K et al.. Severity of Villous Atrophy at Diagnosis in Childhood Does Not Predict Long-term Outcomes in Celiac Disease. J Pediatr Gastroenterol Nutr. 2020;71 (1):71-77. doi: 10.1097/MPG.0000000000002675. PubMed PMID:32097370 .
  16. Sankari, H, Hietikko, M, Kurppa, K, Kaukinen, K, Mansikka, E, Huhtala, H et al.. Intestinal TG3- and TG2-Specific Plasma Cell Responses in Dermatitis Herpetiformis Patients Undergoing a Gluten Challenge. Nutrients. 2020;12 (2):. doi: 10.3390/nu12020467. PubMed PMID:32069794 PubMed Central PMC7071213.
  17. Kalliokoski, S, Mansikka, E, de Kauwe, A, Huhtala, H, Saavalainen, P, Kurppa, K et al.. Gliadin-Induced Ex Vivo T-Cell Response in Dermatitis Herpetiformis: A Predictor of Clinical Relapse on Gluten Challenge?. J Invest Dermatol. 2020;140 (9):1867-1869.e2. doi: 10.1016/j.jid.2019.12.038. PubMed PMID:32035923 .
  18. Repo, M, Rajalahti, T, Hiltunen, P, Sotka, A, Kivelä, L, Huhtala, H et al.. Diagnostic findings and long-term prognosis in children with anemia undergoing GI endoscopies. Gastrointest Endosc. 2020;91 (6):1272-1281.e2. doi: 10.1016/j.gie.2019.12.042. PubMed PMID:31917169 .
  19. Gustafsson, I, Repo, M, Popp, A, Kaukinen, K, Hiltunen, P, Arvola, T et al.. Prevalence and diagnostic outcomes of children with duodenal lesions and negative celiac serology. Dig Liver Dis. 2020;52 (3):289-295. doi: 10.1016/j.dld.2019.11.011. PubMed PMID:31899123 .

Search PubMed

2019

  1. Gustafsson, I, Repo, M, Popp, A, Kaukinen, K, Hiltunen, P, Arvola, T et al.. Prevalence and diagnostic outcomes of children with duodenal lesions and negative celiac serology. Dig Liver Dis. 2020;52 (3):289-295. doi: 10.1016/j.dld.2019.11.011. PubMed PMID:31899123 .
  2. Pohjonen, J, Nurmi, R, Metso, M, Oksanen, P, Huhtala, H, Pörsti, I et al.. Inflammatory bowel disease in patients undergoing renal biopsies. Clin Kidney J. 2019;12 (5):645-651. doi: 10.1093/ckj/sfz004. PubMed PMID:31583091PubMed Central PMC6768292.
  3. Leinonen, H, Kivelä, L, Lähdeaho, ML, Huhtala, H, Kaukinen, K, Kurppa, K et al.. Daily Life Restrictions are Common and Associated with Health Concerns and Dietary Challenges in Adult Celiac Disease Patients Diagnosed in Childhood. Nutrients. 2019;11 (8):. doi: 10.3390/nu11081718. PubMed PMID:31349675PubMed Central PMC6723871.
  4. Pasternack, C, Koskinen, I, Hervonen, K, Kaukinen, K, Järvelin, J, Reunala, T et al.. Risk of fractures in dermatitis herpetiformis and coeliac disease: a register-based study. Scand J Gastroenterol. 2019;54 (7):843-848. doi: 10.1080/00365521.2019.1636132. PubMed PMID:31280614 .
  5. Caetano Dos Santos, FL, Michalek, IM, Laurila, K, Kaukinen, K, Hyttinen, J, Lindfors, K et al.. Automatic classification of IgA endomysial antibody test for celiac disease: a new method deploying machine learning. Sci Rep. 2019;9 (1):9217. doi: 10.1038/s41598-019-45679-x. PubMed PMID:31239486PubMed Central PMC6592927.
  6. Mansikka, E, Hervonen, K, Kaukinen, K, Ilus, T, Oksanen, P, Lindfors, K et al.. Gluten Challenge Induces Skin and Small Bowel Relapse in Long-Term Gluten-Free Diet-Treated Dermatitis Herpetiformis. J Invest Dermatol. 2019;139 (10):2108-2114. doi: 10.1016/j.jid.2019.03.1150. PubMed PMID:30998982 .
  7. Kurppa, K, Fuchs, V, Kaukinen, K. Letter: the end of duodenal biopsies in coeliac disease? Authors’ reply. Aliment Pharmacol Ther. 2019;49 (8):1112. doi: 10.1111/apt.15220. PubMed PMID:30920031 .
  8. Kauma, S, Kaukinen, K, Huhtala, H, Kivelä, L, Pekki, H, Salmi, T et al.. The Phenotype of Celiac Disease Has Low Concordance between Siblings, Despite a Similar Distribution of HLA Haplotypes. Nutrients. 2019;11 (2):. doi: 10.3390/nu11020479. PubMed PMID:30823533 PubMed Central PMC6412523.
  9. Lindfors, K, Ciacci, C, Kurppa, K, Lundin, KEA, Makharia, GK, Mearin, ML et al.. Coeliac disease. Nat Rev Dis Primers. 2019;5 (1):3. doi: 10.1038/s41572-018-0054-z. PubMed PMID:30631077 .
  10. Fuchs, V, Kurppa, K, Huhtala, H, Laurila, K, Mäki, M, Collin, P et al.. Serology-based criteria for adult coeliac disease have excellent accuracy across the range of pre-test probabilities. Aliment Pharmacol Ther. 2019;49 (3):277-284. doi: 10.1111/apt.15109. PubMed PMID:30592070 .
  11. Nurminen, S, Kivelä, L, Huhtala, H, Kaukinen, K, Kurppa, K. Extraintestinal manifestations were common in children with coeliac disease and were more prevalent in patients with more severe clinical and histological presentation. Acta Paediatr. 2019;108 (4):681-687. doi: 10.1111/apa.14324. PubMed PMID:29569302 .
  12. Laurikka, P, Lindfors, K, Oittinen, M, Huhtala, H, Salmi, T, Lähdeaho, ML et al.. Dietary Factors and Mucosal Immune Response in Celiac Disease Patients Having Persistent Symptoms Despite a Gluten-free Diet. J Clin Gastroenterol. 2019;53 (7):507-513. doi: 10.1097/MCG.0000000000001013. PubMed PMID:29505551 .

Search PubMed

2018

  1. Nurmi R, Metso M, Pörsti I, Niemelä O, Huhtala H, Mustonen J, Kaukinen K, Mäkelä S. Celiac disease or positive tissue transglutaminase antibodies in patients undergoing renal biopsies. Dig Liver Dis. 2018 Jan;50(1):27-31. PMID: 29050994
  2. Yohannes DA, Freitag TL, de Kauwe A, Kaukinen K, Kurppa K, Wacklin P, Mäki M, Arstila TP, Anderson RP, Greco D, Saavalainen P. Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease. Sci Rep. 2017 Dec 21;7(1):17977. PMID: 29269859
  3. Elevated serum antiphospholipid antibodies in adults with celiac disease. Laine O, Pitkänen K, Lindfors K, Huhtala H, Niemelä O, Collin P, Kurppa K, Kaukinen K. Dig Liver Dis. 2017 Dec 2. pii: S1590-8658(17)31314-2. PMID: 29258815

2017

  1. Hietikko M, Hervonen K, Ilus T, Salmi T, Huhtala H, Laurila K, Rauhavirta T, Reunala T, Kaukinen K, Lindfors K. Ex vivo Culture of Duodenal Biopsies from Patients with Dermatitis Herpetiformis Indicates that Transglutaminase 3 Antibody Production Occurs in the Gut. Acta Derm Venereol. 2017 Nov 28. PMID: 29182792
  2. Werkstetter KJ, Korponay-Szabó IR, Popp A, Villanacci V, Salemme M, Heilig G, Lillevang ST, Mearin ML, Ribes-Koninckx C, Thomas A, Troncone R, Filipiak B, Mäki M, Gyimesi J, Najafi M, Dolinšek J, Dydensborg Sander S, Auricchio R, Papadopoulou A, Vécsei A, Szitanyi P, Donat E, Nenna R, Alliet P, Penagini F, Garnier-Lengliné H, Castillejo G, Kurppa K, Shamir R, Hauer AC, Smets F, Corujeira S, van Winckel M, Buderus S, Chong S, Husby S, Koletzko S; ProCeDE study group. Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice. Gastroenterology. 2017 Oct;153(4):924-935. PMID: 28624578
  3. Mansikka E, Salmi T, Kaukinen K, Collin P, Huhtala H, Reunala T, Hervonen K. Acta Derm Venereol. 2017 Oct 19. Diagnostic Delay in Dermatitis Herpetiformis in a High-prevalence Area. PMID: 29048096
  4. Hietikko M, Hervonen K, Salmi T, Ilus T, Zone JJ, Kaukinen K, Reunala T, Lindfors K. Disappearance of epidermal transglutaminase and IgA deposits from the papillary dermis of dermatitis herpetiformis patients after a long-term gluten-free diet. Br J Dermatol. 2017 Sep 14. PMID: 28906552
  5. Heikkilä K, Rissanen H, Heliövaara M, Knekt P, Mäki M, Kaukinen K. Associations of tissue transglutaminase antibody seropositivity with coronary heart disease: Findings from a prospective cohort study. Nutr Metab Cardiovasc Dis. 2017 Jun 15. PMID:28756971
  6. Aaltonen K, Laurikka P, Huhtala H, Mäki M, Kaukinen K, Kurppa K. The Long-Term Consumption of Oats in Celiac Disease Patients Is Safe: A Large Cross-Sectional Study. Nutrients. 2017 Jun 15;9(6). PMID:28617328
  7. Garber ME, Saldanha A, Parker JS, Jones WD, Kaukinen K, Laurila K, Lähdeaho ML, Khatri P, Khosla C, Adelman DC, Mäki M. A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease. Cell Mol Gastroenterol Hepatol. 2017 Jan 28;4(1):1-17. PMID:28508029
  8. Laurikka P, Kaukinen K, Kurppa K. Unravelling the mechanisms behind the persistent gastrointestinal symptoms in celiac disease – how can they lead to better treatment outcomes? Expert Rev Gastroenterol Hepatol. 2017 Jul;11(7):605-607. PMID:28347161
  9. Pekki H, Kurppa K, Mäki M, Huhtala H, Laurila K, Ilus T, Kaukinen K. Performing routine follow-up biopsy 1 year after diagnosis does not affect long-term outcomes in coeliac disease. Aliment Pharmacol Ther. 2017 Jun;45(11):1459-1468. PMID:28326597
  10. Di Cicco E, Ferguson HW, Schulze AD, Kaukinen KH, Li S, Vanderstichel R, Wessel Ø, Rimstad E, Gardner IA, Hammell KL, Miller KM. Heart and skeletal muscle inflammation (HSMI) disease diagnosed on a British Columbia salmon farm through a longitudinal farm study. PLoS One. 2017 Feb 22;12(2):e0171471. PMID:28225783
  11. Kivelä L, Kaukinen K, Huhtala H, Lähdeaho ML, Mäki M, Kurppa K. At-Risk Screened Children with Celiac Disease are Comparable in Disease Severity and Dietary Adherence to Those Found because of Clinical Suspicion: A Large Cohort Study. J Pediatr. 2017 Apr;183:115-121.e2. PMID:28153477
  12. Laitinen AU, Agardh D, Kivelä L, Huhtala H, Lähdeaho ML, Kaukinen K, Kurppa K. Coeliac patients detected during type 1 diabetes surveillance had similar issues to those diagnosed on a clinical basis. Acta Paediatr. 2017 Apr;106(4):639-646. PMID:27935157
  13. Oittinen M, Popp A, Kurppa K, Lindfors K, Mäki M, Kaikkonen MU, Viiri K. Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia. Stem Cells. 2017 Feb;35(2):445-457. PMID:27570105

2016

  1. Hervonen K, Salmi TT, Ilus T, Paasikivi K, Vornanen M, Laurila K, Lindfors K, Viiri K, Saavalainen P, Collin P, Kaukinen K, Reunala T. Dermatitis Herpetiformis Refractory to Gluten-free Dietary Treatment. Acta Derm Venereol 2016;96:82-6. PMID:26084552
  2. Salmi TT, Kurppa K, Hervonen K, Laurila K, Collin P, Huhtala H, Saavalainen P, Sievänen H, Reunala T, Kaukinen K. Serum transglutaminase 3 antibodies correlate with age at celiac disease diagnosis. Dig Liver Dis 2016;48:632-7 . PMID:27026081
  3. Pasternack C, Kaukinen K, Kurppa K, Mäki M, Collin P, Hervonen K, Reunala T, Huhtala H, Kekkonen L, Salmi T. Gastrointestinal Symptoms Increase the Burden of Illness in Dermatitis Herpetiformis: A Prospective Study. Acta Derm Venereol 2016 (E-pub ahead of print) doi: 10.2340/00015555-2471. PMID:27241271
  4. Kalliokoski S, Ortín Piqueras V, Frías R, Sulic AM, Määttä JAE, Kähkönen N, Viiri K, Huhtala H, Pasternack A, Laurila K, Sblattero D, Korponay-Szabó IR, Mäki M, Caja S, Kaukinen K, Lindfors K. Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice. Amino acids 2016, in press DOI:10.1007/s00726-016-2306-0. PMID:27503559
  5. Ciacci C, Ciclitira P, Hadjivassiliou M, Kaukinen K, Ludvigsson JF, McGough N, Sanders DS, Woodward J, Leonard JN, Swift GL. Safety of gluten in gluten-free foods. Response to Forbes’s comment. United European Gastroenterol Journal 2016;4:153. PMID:26966536
  6. Di Niro R, Snir O, Kaukinen K, Yaari G, Lundin KE, Gupta NT, Kleinstein SH, Cols M, Cerutti A, Mäki M, Shlomchik MJ, Sollid LM. Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease. Mucosal Immunol 2016;9:254-64. PMID:26153762
  7. Nylund L, Kaukinen K, Lindfors K. The microbiota as a component of the celiac disease and non-celiac gluten sensitivity. Clin Nutr Experimental 2016;6:17-24.
  8. Kurppa K, Taavela J, Saavalainen P, Kaukinen K, Lindfors K. Novel diagnostic techniques for celiac disease. Expert Rev Gastroenterol Hepatol 2016;10:795-805 . PMID:26838683
  9. Repo M, Lindfors K, Mäki M, Huhtala H, Laurila K, Lähdeaho ML, Saavalainen P, Kaukinen K, Kurppa K. Anemia and iron deficiency in children with potential celiac disease. J Pediatr Gastroenterol Nutr 2016; in press, DOI:10.1097/MPG.0000000000001234.. PMID:27101536
  10. Rajalahti T, Repo M, Kivelä L, Huhtala H, Mäki M, Kaukinen K, Lindfors K, Kurppa K. Anemia in Pediatric Celiac Disease: Association with Clinical and Histological Features and Response to Gluten-free Diet. J Pediatr Gastroenterol Nutr 2016 (Epub ahead of print). DOI:10.1097/MPG.0000000000001221. PMID:27035377
  11. Saukkonen J, Kaukinen K, Koivisto AM, Mäki M, Laurila K, Sievänen H, Collin P, Kurppa K. Clinical characteristics and the dietary response in celiac disease patients presenting with or without anemia. J Clin Gastroenterol. 2016 (Epub ahead of print). DOI:10.1097/MCG.0000000000000556.. PMID:27306936
  12. Mansikka E, Hervonen K, Salmi TT, Kautiainen H, Kaukinen K, Collin P, Reunala T. The Decreasing Prevalence of Severe Villous atrophy in dermatitis herpetiformis: A 45-year experience in 393 patients. J Clin Gastroenterol. 2016 (Epub ahead of print). DOI:10.1097/MCG.0000000000000533. PMID:27136959
  13. Äärelä L, Nurminen S, Kivekä L, Huhtala H, Mäki M, Viitasalo A, Kaukinen K, Lakka T, Kurppa K. Prevalence and associated factors of abnormal liver values in children with celiac disease. Dig Liv Dis, in press 2016 http://dx.doi.org/10.1016/j.dld.2016.05.022. PMID:27338852
  14. Kylökäs A, Kaukinen K, Huhtala H, Collin P, Mäki M, Kurppa K. Type 1 and type 2 diabetes in celiac disease: prevalence and effect on clinical and histological presentation. BMC Gastroenterol 2016;16:76. PMID:27457377
  15. Laurikka P, Salmi T, Collin P, Huhtala H, Mäki M, Kaukinen K, Kurppa K. Gastrointestinal Symptoms in Celiac Disease Patients on a Long-Term Gluten-Free Diet. Nutrients 2016;8:429. PMID:27428994
  16. Collin P, Salmi TT, Hervonen K, Kaukinen K, Reunala T. Dermatitis herpetiformis: a cutaneus manifestation of coeliac disease. Ann Med 2016, in press. DOI:10.1080/07853890.2016.1222450 PMID:27499257

2015

  1. Pekki H, Kurppa K, Mäki M, Huhtala H, Sievänen H, Laurila K, Collin P, Kaukinen K. Predictors and Significance of Incomplete Mucosal Recovery in Celiac Disease After 1 Year on a Gluten-Free Diet. Am J Gastroenterol 2015;110:1078-85.
  2. Kalliokoski S, Caja S, Frias R, Laurila K, Koskinen O, Niemelä O, Mäki M, Kaukinen K, Korponay-Szabo IR, Lindfors K. Injection of celiac patient serum or immunoglobulins to mice reproduces a condition mimicking early developing celiac disease. J Mol Med 2015;93:51-62.
  3. See JA, Kaukinen K, Makharia GK, Gibson PR, Murray JA. Practical insights into gluten-free diets Nat Rev Gastroenterol Hepatol 2015;12:580-91.
  4. Pasternack C, Kaukinen K, Kurppa K, Mäki M, Collin P, Reunala T, Huhtala H, Salmi T. Quality of Life and Gastrointestinal Symptoms in Long-Term Treated Dermatitis Herpetiformis Patients: A Cross-Sectional Study in Finland. Am J Clin Dermatol 2015;16:545-52.
  5. Nurminen S, Kivelä L, Taavela J, Huhtala H, Mäki M, Kaukinen K, Kurppa K. Factors associated with growth disturbance at celiac disease diagnosis in children: a retrospective cohort study. BMC Gastroenterology 2015;15:125
  6. Kivelä L, Kaukinen K, Lähdeaho ML, Huhtala H, Ashorn M, Ruuska T, Hiltunen P, Visakorpi J, Mäki M, Kurppa K. Presentation of Celiac Disease in Finnish Children Is No Longer Changing: A 50-Year Perspective. J Pediatr 2015;167:1109-15.e1
  7. Lindfors K, Kurppa K, Koskinen O, Kaukinen K. Celiaki – från bättre diagnostik till god behandling. Finska läkaresällskapets handlingar 2015;175:38-44.
  8. Reunala T, Salmi TT, Hervonen K, Laurila K, Kautianen H, Collin P, Kaukinen K. IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis: a significant but not complete response to g gluten-free diet treatment. Br J Dermatol 2015;172:1139-41
  9. Heikkilä K, Mäki M, Kaukinen K. Coeliac disease and the risk of bone fractures: a systematic review and meta-analysi. J Clin Endocr Metab 2015;100:25-34.
  10. Heikkilä K, Heliövaara M, Impivaara O, Kröger H, Knekt P, Rissanen H, Mäki M, Kaukinen K. Coeliac disease autoimminity and hip fracture risk: findings from a prospective cohort study. J Bone Miner Res 2015;30:630-6.
  11. Kurppa K, Collin P, Mäki M, Kaukinen K. Reasons for caution before screening for celiac disease, reply. Gastroenterology 2015;148:261-2.
  12. Ludvigsson JF, Card TR, Kaukinen K, Bai J, Zingone F, Sanders DS, Murray JA. Screening for coeliac disease in the general population and in high-risk groups. United European Gastroenterology Journal 2015;3:106-20.
  13. Ciacci C, Ciclitira P, Hadjivassiliou M, Kaukinen K, Ludvigsson JF, McCough N, Sanders DS, Woodward J, Swift GL Gluten-free diet: a review of the literature. United European Gastroenterology Journal 2015;3:121-35.
  14. Kaukinen K, Lindfors K. Novel treatments for celiac disease: glutenases and beyond. Dig Dis 2015;33:277-81.
  15. Reunala T, Salmi TT, Hervonen K. Dermatitis Herpetiformis: Pathognomonic Transglutaminase IgA Deposits in the Skin and Excellent Prognosis on a Gluten-free Diet. Acta Derm Venereol 2015;95:997-22.
  16. Sulic AM, Kurppa K, Rauhavirta T, Kaukinen K, Lindfors K. Trasglutaminase as therapeutic target for celiac disease. Expert Opin Ther Targets 2015;19:335-48.
  17. Wacklin P, Laurikka P, Lindfors K, Mättö J, Kurppa K, Kaukinen K. Dysbiosis in celiac disease patients with persistent symptoms on gluten-free diet: a condition similar to that present in irritable bowel syndrome patients? Reply. Am J Gastroenterol 2015;110:598-9.
  18. Heikkilä K, Koskinen OA, Agarwal A, Tikkinen K, Mäki M, Kaukinen K. Associations of coeliac disease with coronary heart disease and cerebrovascular disease: A systematic review and meta-analysis. Nutr Metab Cardiovasc Dis 2015;25:816-31.
  19. Kinnunen U, Vuopala K, Kaukinen K. Autoimmune enteropathy. Duodecim 2015;131:533-40.
  20. Salmi TT, Hervonen K, Kurppa K, Collin P, Kaukinen K, Reunala T. Coeliac disease evolving into dermatitis herpetiformis in patients adhering to normal or gluten-free diet. Scand J Gastroenterol 2015;50:387-92.

2014

  1. Kaukinen K, Lindfors K, Mäki M Advances in the treatment of coeliac disease: immunopathogenic perspective. Nat Rev Gastroenterol Hepatol 2014;11:36-44
  2. Ilus T, Kaukinen K, Virta LJ, Pukkala E, Collin P. Incidence of malignancies in diagnosed celiac disease patients: a population-based estimate. Am J Gastroenterol 2014;104:1471-1477
  3. Wacklin P, Laurikka P, Lindfors K, Colli P, Salmi T, Lähdeaho ML, Saavalainen P, Mäki M, Mättö J, Kurppa K, Kaukinen K. Altered duodenal microbiota composition in celiac disease patients suffering from persistent symptoms on a long-term gluten-free diet. Am J Gastroenterol 2014;109:1933-41.
  4. Kaukinen K, Mäki M. Coeliac disease in 2013: new insights in dietary gluten-induced autoimmunity. Nat Rev Gastroenterol Hepatol 2014;11:80-2.
  5. Ilus T, Kaukinen K, Virta LJ, Huhtala H, Mäki M, Kurppa K, Heikkinen M, Heikura M, Hirsi E, Jantunen K, Moilanen V, Nielsen C, Puhto M, Pölkki H, Vihriälä I, Collin P. Refractory celiac disease in a country with a high prevalence of clinically diagnosed coeliac disease. Aliment Pharm Ther 2014;39:418-25.
  6. Kurppa K, Paavola A, Collin P, Sievänen H, Laurila K, Huhtala H, Saavalainen P, Mäki M, Kaukinen K. Benefits of gluten-free diet for asymptomatic patients with serologic markers of celiac disease. Gastroenterology 2014;147:610-7. With editorial
  7. Lähdeaho ML, Kaukinen K, Laurila K, Vuotikak P, Koivurova OP, Kärjä-Lahdensuu T, Marcantonio A, Adelman DC, Mäki M. Attenuation of gluten-induced duodenal mucosla injury in celiac disease: results of a randomized controlled Phase 2 clinical trial of a novel gluteinase ALV003. Gastroneterology 2014;146:1649-58. with editorial
  8. Nadalutti CA, Korponay-Szabo IR, Kaukinen K, Griffin M, Mäki M, Lindfors K. Celiac disease patient IgA antibodies induce endothelial adhesion and cell polarization deficts via extracellular transglutaminase 2. Cell mol Life Sci 2014;71:1315-26.
  9. Spatola BN, Kaukinen K, Collin P, Mäki M, Kagnoff M, Daugherty PS. Maintenanceof deamidated gliadin peptide antibodies on a gluten-free diet indicated non-responsive celiac disease. Aliment Pharm Ther 2014;39:407-17.
  10. Viitasalo L, Niemi L, Ashorn M, Ashorn S, Braun J, Huhtala H, Collin P, Mäki M, Kaukinen K, Kurppa K, Iltanen S. Early microbial markers of celiac disease. J Clin Gastroenterol 2014;48:620-4. With editorial
  11. Hervonen K, Salmi TT, Kurppa K, Kaukinen K, Collin P, Reunala T. Dermatitis herpetiformis in children: a long-term follow-up study. Br J Dermatol 2014,171:1242-3.
  12. Fuchs V, Kurppa K, Huhtala H, Mäki M, Kaukinen K. Factors associated with diagnostic delay in celiac disease. Scand J Gastroenterol 2014,49:1304-10.
  13. Collin P, ilus T, Kaukinen K. Refractory coeliac disease- rigorous management revealing, or resulting in, rarity? Reply: Aliment Pharm Ther 2014;39:639.
  14. Kaukinen K, Daugherty PS. Nonresponsive coeliac disease and evaluation of the strictness of a gluten-free diet, Reply. Aliment Pharm Ther 2014;39:1242
  15. Salmi TT, Hervonen K, Koskinen O, Huhtala H, Laurila K, Mäki M, Collin P, Kaukinen K, Reunala T. Small bowel mucosal transglutaminase 2-specific IgA deposits in dermatitis herpetiformis. Acta Dermatol-Venerologica 2014;94:393-7.
  16. Kurppa K, Hietikko M, Sulic AM, Kaukinen K, Lindfors K. Current status of drugs in development for celiac disease. Exp Opin Investig Drug 2014;23:1079-91.
  17. Rauhavirta T, Lindfors K, Koskinen O, Laurila K, Kurppa K, Saavalainen P, Mäki M, Collin P, Kaukinen K. Impaired epithelial integrity in the duodenal mucosa at early stages of celiac disease. Transl Res 2014;164:223-31.
  18. Kaukinen K, Collin P. Oireita viljoista ilman keliakiaa – mitä gluteeniherkkyydestä tiedetään. Lääkärilehti 2014; 69:531-2.
  19. Ludvigsson JF, Bai JC, Biagi F, Card TR, Ciacci C, Ciclitira PJ, Green PH, Hadjivassiliou M, Holdoway A, van Heel DA, Kaukinen K, Leffler DA, Leonard JN, Lundin KE, McGough N, Davidson M, Murray JA, Swift GL, Walker MM, Zingone F, Sanders DS. Authors of the BSG Coeliac Disease Guidelines Development Group. Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology. Gut 2014;63:1210-28.

2013

  1. Kaukinen K, Collin P, Huhtala H, Mäki M. Long-term consumption of oats in adult celiac disease patients. Nutrients 2013;5:4380-9.
  2. Ludvigsson JF, Leffler DA, Bai J, Biagi F, Fasano A, Green P, Hadjivassiliou M, Kaukinen K, Kelly C, Leonard JN, Lundin K, Murray JA, Sanders D, Walker MM, Zingone F, Ciacci C. The Oslo definitions for coeliac disease 1 and related terms. Gut 2013;62:43-52.
  3. Wacklin P, Kaukinen K, Tuovinen E, Lindfors K, Collin P, Partanen J, Mäki M, Mättö J. The duodenal microbiota composition of adult celiac disease patients is associated to the clinical manifestation of the disease. Inflamm Bowel Dis 2013;19:934-41.
  4. Ballew JT, Murray JA, Collin P, Mäki M, Kagnoff MF, Kaukinen K, Daugherty PS. Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes. Proc Natl Acad Sci USA 2013;110:19330-5.
  5. Ruuskanen A, Kaukinen K, Collin P, Krekelä I, Patrikainen H, Tillonen J, Nyrke T, Laurila K, Haimila K, Partanen J, Valve R, Mäki M, Luostarinen L. Gliadin antibodies in older population and neurological and psychiatric disorders. Acta Neurol Scand 2013;127:19-25.
  6. Rauhavirta T, Oittinen M, Kivistö R, Männistö PT, Garcia-Horsman AJ, Wang Z, Griffin M, Mäki M, Kaukinen K, Lindfors K. Are transglutaminase 2 inhibitors able to reduce gliadin-induced toxicity related to celiac disease? A proof-of-concept study. J Clin Immunol 2013;33:134-42.
  7. Kalliokoski S, Sulic AM, Korponay-Szabó IR, Szondy Z, Frias R, Alea Perez M, Martucciello S, Roivainen A, Pelliniemi LJ, Esposito C, Griffin M, Sblattero D, Mäki M, Kaukinen K, Lindfors K, Caja S. Celiac disease–specific TG2-targeted autoantibodies inhibit angiogenesis in vitro and in vivo by modulating extracellular matrix. Plos One 2013;8:e65887.
  8. Mattila E, Kurppa K, Ukkola A, Collin P, Huhtala H, Forma L, Lähdeaho ML, Kekkonen L, Mäki M, Kaukinen K. Burden of illness and use of health care services before and after celiac disease diagnosis in childrem, J Pediatr Gastroenterol Nutr 2013; 57:53-6.
  9. Hadjivassiliou M, Aeschlimann P, Sanders DS, Mäki M, Kaukinen K, Grünewald RA, Bandmann O, Woodroofe N, Haddock G, Aeschlimann DP. Transglutaminase 6 antibodies in the diagnosis of gluten ataxia. Neurology 2013;80:1740-45.
  10. Paarlahti P, Kurppa K, Ukkola A, Collin P, Huhtala H, Mäki M, Kaukinen K. Predictors of perisistent symptoms and reduced quality of life in treated coeliac disease patients: a large cross-sectional study. BMC Gastroenterol 2013, 13:75.
  11. Lameris AL, Huybers S, Kaukinen K, Mäkelä TH, Bindels RJ, Hoenderop JG, Nevalainen PI. Expression profiling of claudins in the human gastrointestinal tract in health and during inflammatory bowel disease. Scand J Gastroenterol 2013;48:58-69.
  12. Taavela J, Koskinen O, Huhtala H, Lähdeaho ML, Popp A, Laurila K, Collin P, Kaukinen K, Kurppa K, Mäki M. Validation of morphometric analyses of small-intestinal biopsy readouts in celiac disease. 2013;8:e76163.
  13. Spatola BN, Murray JA, Kagnoff M, Kaukinen K, Daugherty PS. Antibody repertoire profiling using bacterial display identifies reactivity signatures of celiac disease. Anal Chem 2013;85:1215-22.
  14. Collin P, Kaukinen K. Celiac disease: clinch the diagnosis when it is just around the corner. Dig Dis Sci 2013;58:1165-6.
  15. Kaukinen K, Mäki M, Collin P. Gluteeniherkkyys ilman keliakiaa – faktaa vai fiktiota (Gluten-sensitivity without celiac disease –fact or fiction?). Duodecim 2013:129:1742-3.
  16. Kaukinen K, Mäki M, Collin P. Gluteenin välttäminen vai gluteeniton ruokavalio? – kommentti. (Gluten avoidance or gluten-free diet –commentary) Duodecim 2013;129:2403.
  17. Taavela J, Kurppa K, Collin P, Lähdeaho ML,Salmi T, Saavalainen P, Partanen J, Haimila K, Huhtala H, Laurila K, Sievänen H, Mäki M, Kaukinen K. Small-bowel mucosal damage and serology associate to patient-reported and other clinical outcomes in celiac disease. Clin Gas Hepatol 2013;11:166-71.
  18. Nadalutti AC, Korponay-Szabo IR, Kaukinen K, Wang Z, Griffin M, Mäki M, Lindfors K. Thioredoxin is involved in endothelial cell extracellular transglutaminase 2 activation mediated by celiac disease patient IgA. Plos One 2013;8:e77277.
  19. Wang Z, Perez M, Caja S, Melino G, Johnson TS, Lindfors K, Griffin M A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis. Cell Death Dis. 2013;4:e808.